李宗璘
姓名 李宗璘
電子郵件
聯絡電話 02-27871235
現任 研究員
職稱 中心副主任
E-mail tlli@gate.sinica.edu.tw
電話 02-27871235
現任 研究員
E-mail tlli@gate.sinica.edu.tw
電話 02-27871235
職稱 研究員
現任 學術副主任
E-mail tlli@gate.sinica.edu.tw
電話 02-27871235
年度 論文名稱
2025 Y. L. Chan, J. C. Liao, T. L. Li, C. J. Wu*, Y. H. Chiu*, Bifidobacterium lactis ameliorates AOM/DSS‑induced inflammation, dysbiosis, and colonic precancerous lesions, APPLIED MICROBIAL AND CELL PHYSIOLOGY, vol. 109 (69), 1-15, 2025
2025 H. T. Huanga, C. T. Chioua, Y. C. Lin, L. J. Zhang, C. H. Chao, P. J. Sung, J. J. Chen, T. L. Li, I. W. Lo*, C. C. Liaw*, Potential Anti-H1N1 Schtriterpenoids from Kadsura japonica L. Vines, PHYTOCHEMISTRY, 2025
2024 S. P. Selvaraj, K. H. Lin, W. C. Lin, M. F. You, T. L. Li*, J. Y Chen*, Rejuvenation of Meropenem by Conjugation with Tilapia Piscidin-4 Peptide Targeting NDM-1 Escherichia coli, ACS OMEGA, vol. 28;9(27):29756-29764, 2024
2024 H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, Y. S. Lin, L. J. Zhang, T. L. Li, C. C. Liaw*, Y. H. Kuo*, Kaguacidine A: a novel spirohydantoin-containing cucurbitane glycoside from vines of Momordica charantia L., NATURAL PRODUCT RESEARCH, vol. 38 (13), 2179-2186, 2024
2023 H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, Y. S. Lin, L. J. Zhang, T. L. Li, C. Ching Liaw*, Y. H. Kuo*, Kaguacidine A: a novel spirohydantoin-containing cucurbitane glycoside from vines of Momordica charantia, NATURAL PRODUCT RESEARCH, vol. 38(13):2179-2186, 2023
2023 Y. L. Wang, C. Y. Chang, N. S. Hsu, I. W. Lo, K. H. Lin, C. L. Chen, C. F. Chang, Z. C. Wang, Y. Ogasawara, T. Dairi, C. Maruyama, Y. Hamano*, T. L. Li*, N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry, NATURE COMMUNICATIONS, vol. 14:2528, 1-14, 2023
2023 S. S. Chang, H. T. Huang, W. C. Wei, I. W. Lo, Y. C. Lin, C. H. Chao, G. Y. Liao, Y. C. Shen, J. J. Chen, T. L. Li, L. T. Lin, C. J. Tai, Y. H. Kuo, C. C. Liaw*, Anti-inflammatory Effect of Euphane-and Tirucallane-type Triterpenes Isolated from Traditional Herb Euphorbia neriifolia L, FRONTIERS IN CHEMISTRY, vol. 11, 1-13, 10.3389/fchem.2023.1, 2023
2023 S. H. Liu, H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, C. H. Chao, H. C. Huang, F. R. Chang, T. L. Li, Y. C. Shen, C. C. Liao*, Potential natural product 3,4-seco-schitriterpenoids from Kadsura japonica L. as anti-neuroinflammatory agents, BIOORGANIC CHEMISTRY, vol. 141, 106843, 2023
2023 H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, Y. S. Lin, L. J. Zhang, C. Ching Liaw*, Y. H. Kuo*, Kaguacidine A: a novel spirohydantoin-containing cucurbitane glycoside from vines of Momordica charantia, NATURAL PRODUCT RESEARCH, vol. DOI:10.1080/14786419.202, 1-8, 2023
2023 Y. L. Wang, C. Y. Chang, N. S. Hsu, I. W. Lo, K. H. Lin, C. L. Chen, C. F. Chang, Z. C. Wang, Y. Ogasawara, T. Dairi, C. Maruyama, Y. Hamano*, N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry, NATURE COMMUNICATIONS, vol. 14:2528 (doi.org/10.1038/s41467-023-38218-w), 1-14, 2023
2022 M. H. Chen, Y. S. Li, N. S. Hsu, K. H. Lin, Y. L. Wang, Z. C. Wang, C. F. Chang, J. P. Lin, C. Y. Chang, T. L. Li*, Structural and mechanistic bases for StnK3 and its mutants-mediated Lewis-acid-dependent epimerization and retro aldol reactions, ACS CATALYSIS, vol. 12, 1945-1956, 2022
2022 R. Rattinam, R. S. Basha, Y. L. Wang, Z. C. Wang, N. S. Hsu, K. H. Lin, S. Malek Zadeh, K. Adhikari, J. P. Lin, T. L. Li*, KasQ an epimerase primes the biosynthesis of aminoglycoside antibiotic kasugamycin and KasF/H acetyltransferases inactivate its activity, BIOMEDICINES, vol. 10(2), 212, 2022
2022 B. R. Chen, W. M. Li, T. L. Li, Y. L. Chan, C. J. Wu*, Fucoidan from Sargassum hemiphyllum inhibits infection and inflammation of Helicobacter pylori, SCIENTIFIC REPORTS, vol. 12(1), 429, 2022
2022 Y. C. Pan, Y. L. Wang, S. I. Toh, N. S. Hsu, K. H. Lin, Z. Xu, S. C. Huang, T. K. Wu, T. L. Li, C. Y. Chang*, Dual-mechanism confers self-resistance to the antituberculosis antibiotic capreomycin, ACS CHEMICAL BIOLOGY, vol. 17(1), 138-146, 2022
2022 C. C. Liaw, I. W. Lo, Y. C. Lin, H. T. Huang, L. J. Zhang, P. C. Hsiao, T. L. Li, * Y. H. Kuo*, Four cucurbitane glycosides taimordisins A–D with novel furopyranone skeletons isolated from the fruits of Momordica charantia, FOOD CHEMISTRY: X, vol. 14, 100286, 2022
2022 S. M. Zadeh, M. H. Chen, Z. C. Wang, E. K. Astani, I. W. Lo, K. H. Lin, N. S. Hsu, K. Adhikari, S. Y. Lyu, H. Y. Tsai, Y. Terasawa, M. Yabe, K. Yamamoto, S. Ichikawa, T. L. Li*, β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin, COMMUNICATIONS CHEMISTRY, vol. 5, 87, 1-16, 2022
2022 E. Astani, S. M. Zadeh, N. S. Hsu, K. H. Lin, S. Sardari, T. L. Li*, Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYcb-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations, ACS OMEGA, vol. 7(37), 32970-32987, 2022
2022 Z. C. Wang, I. W. Lo, K. H. Lin, A. N. Cheng, S. M. Zadeh, Y. H. Huang, T. L. Li*, Genetic and biochemical characterization of halogenation and drug-transportation genes encoded in the albofungin biosynthetic gene cluster, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 88(17):e0080622, 1-20, 2022
2022 I. W. Lo, G. Y. Liao, J. C. Lee, C. I. Chang, Y. C. Wu, S. P. Liu, H. J. Su, C. I. Liu, C. Y. Kuo, Z.Y. Lin, T. L. Li*, Y. S. Lin*, C. C. Liaw*, Novel Aporphine- and Proaporphine-Clerodane Hybrids Identified from the Barks of Taiwanese Polyalthia Longifolia var. pendula with Strong Anti-DENV2 Activity, PHARMACEUTICS, vol. 15(10), 1218, 1-15, 2022
2022 H. T. Huang, I. W. Lo, G. Y. Liao, Y. C. Lin, Y. C. Shen, H. C. Huang, T. L. Li, K. T. Lee, Y. H. Kuo*, C. C. Liaw*, Anti-inflammatory sesquiterpene and triterpene acids from Mesona procumbens Hemsley, FRONTIERS IN CHEMISTRY, vol. 10:1003356, 1-13, 2022
2022 M. H. Chen, Y. S. Li, N. S. Hsu, K. H. Lin, Y. L. Wang, Z. C. Wang, C. F. Chang, J. P. Lin, C. Y. Chang, Structural and mechanistic bases for StnK3 and its mutants-mediated Lewis-acid-dependent epimerization and retro aldol reactions, ACS CATALYSIS, vol. 12, 1945-1956, 2022
2022 R. Rattinam, R. S. Basha, Y. L. Wang, Z. C. Wang, N. S. Hsu, K. H. Lin, S. Malek Zadeh, K. Adhikari, J. P. Lin, KasQ an epimerase primes the biosynthesis of aminoglycoside antibiotic kasugamycin and KasF/H acetyltransferases inactivate its activity, BIOMEDICINES, vol. 10(2), 212, 2022
2022 B. R. Chen, W. M. Li, Y. L. Chan, C. J. Wu*, Fucoidan from Sargassum hemiphyllum inhibits infection and inflammation of Helicobacter pylori, SCIENTIFIC REPORTS, vol. 12(1), 429, 2022
2022 Y. C. Pan, Y. L. Wang, S. I. Toh, N. S. Hsu, K. H. Lin, Z. Xu, S. C. Huang, T. K. Wu, C. Y. Chang*, Dual-mechanism confers self-resistance to the antituberculosis antibiotic capreomycin, ACS CHEMICAL BIOLOGY, vol. 17(1), 138-146, 2022
2022 C. C. Liaw, I. W. Lo, Y. C. Lin, H. T. Huang, L. J. Zhang, P. C. Hsiao, * Y. H. Kuo*, Four cucurbitane glycosides taimordisins A–D with novel furopyranone skeletons isolated from the fruits of Momordica charantia, FOOD CHEMISTRY: X, vol. 14, 100286, 2022
2022 S. M. Zadeh, M. H. Chen, Z. C. Wang, E. K. Astani, I. W. Lo, K. H. Lin, N. S. Hsu, K. Adhikari, S. Y. Lyu, H. Y. Tsai, Y. Terasawa, M. Yabe, K. Yamamoto, S. Ichikawa, β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin, COMMUNICATIONS CHEMISTRY, vol. 5, 87, 1-16, 2022
2022 E. Astani, S. M. Zadeh, N. S. Hsu, K. H. Lin, S. Sardari, Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYcb-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations, ACS OMEGA, vol. 7(37), 32970-32987, 2022
2022 Z. C. Wang, I. W. Lo, K. H. Lin, A. N. Cheng, S. M. Zadeh, Y. H. Huang, Genetic and biochemical characterization of halogenation and drug-transportation genes encoded in the albofungin biosynthetic gene cluster, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 88(17):e0080622, 1-20, 2022
2022 I. W. Lo, G. Y. Liao, J. C. Lee, C. I. Chang, Y. C. Wu, S. P. Liu, H. J. Su, C. I. Liu, C. Y. Kuo, Z.Y. Lin, T. L. Li*, Y. S. Lin*, C. C. Liaw*, Novel Aporphine- and Proaporphine-Clerodane Hybrids Identified from the Barks of Taiwanese Polyalthia Longifolia var. pendula with Strong Anti-DENV2 Activity, PHARMACEUTICS, vol. 15(10), 1218, 1-15, 2022
2022 H. T. Huang, I. W. Lo, G. Y. Liao, Y. C. Lin, Y. C. Shen, H. C. Huang, K. T. Lee, Y. H. Kuo*, C. C. Liaw*, Anti-inflammatory sesquiterpene and triterpene acids from Mesona procumbens Hemsley, FRONTIERS IN CHEMISTRY, vol. 10:1003356, 1-13, 2022
2021 T. S. A. Wang*, R. Y. Wu, Y. Hong, Z. C. Wang, T. L. Li, J. J. Shie, C. C. Hsu, Labeling and characterization of phenol‐containing glycopeptides using chemoselective probes with isotope tags, CHEMBIOCHEM, vol. 22(14), 2415-2419, 2021
2021 B. R. Chen, K. T. Hsu, W. H. Hsu, B. H. Lee, T. L. Li, Y. L. Chan, C. J. Wu*, Immunomodulation and mechanisms of fucoidan from Cladosiphon okamuranus ameliorates atopic dermatitis symptoms, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, vol. 189, 537-543, 2021
2021 B. R. Chen, K. T. Hsu, T. L. Li, Y. L. Chan, C. J. Wu*, Topical application of fucoidan derived from Cladosiphon okamuranus alleviates atopic dermatitis symptoms through immunomodulation, INTERNATIONAL IMMUNOPHARMACOLOGY, vol. 101, 108362, 2021
2021 T. S. A. Wang*, R. Y. Wu, Y. Hong, Z. C. Wang, J. J. Shie, C. C. Hsu, Labeling and characterization of phenol‐containing glycopeptides using chemoselective probes with isotope tags, CHEMBIOCHEM, vol. 22(14), 2415-2419, 2021
2021 B. R. Chen, K. T. Hsu, W. H. Hsu, B. H. Lee, Y. L. Chan, C. J. Wu*, Immunomodulation and mechanisms of fucoidan from Cladosiphon okamuranus ameliorates atopic dermatitis symptoms, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, vol. 189, 537-543, 2021
2021 B. R. Chen, K. T. Hsu, Y. L. Chan, C. J. Wu*, Topical application of fucoidan derived from Cladosiphon okamuranus alleviates atopic dermatitis symptoms through immunomodulation, INTERNATIONAL IMMUNOPHARMACOLOGY, vol. 101, 108362, 2021
2020 K. H. Lin, S. Y. Lyu, H. W. Yeh, Y. S. Li, N. S. Hsu, C. M. Huang, Y. L. Wang, H. W. Shih, Z. C. Wang, C. J. Wu, T. L. Li*, Structural and chemical trapping of short-lived flavin-oxide intermediates reveals substrate-directed reaction multiplicity, PROTEIN SCIENCE, vol. 29, 1655-1666, 2020
2020 K. Adhikari, I. W. Lo, C. L. Chen, Y. L. Wang, K. H. Lin, S. Malek Zadeh, R. Rattinam, Y. S. Li, C. J. Wu, T. L. Li*, Chemoenzymatic synthesis and biological evaluation for bioactive molecules derived from bacterial benzoyl coenzyme A ligase and plant type III polyketide synthase, BIOMOLECULES, vol. 10(5), 738, 2020
2020 S. Malek Zadeh, E. Astani, Z. C. Wang, K. Adhikari, R. Rattinam, T. L. Li*, Theoretical study of intermolecular interactions between critical residues of membrane protein MraYAA and Promising Antibiotic Muraymycin D2, ACS OMEGA, vol. 5(36), 22739–22749, 2020
2020 Y. M. Liu, T. H. Wu, Y. H. Chiu, H. Wang, T. L. Li, S. Hsia, Y. L. Chan*, C. J. Wu*, Positive effects of preventive nutrition supplement on anticancer radiotherapy in lung cancer bearing mice, CANCERS, vol. 12(9), 2445, 2020
2020 K. H. Lin, S. Y. Lyu, H. W. Yeh, Y. S. Li, N. S. Hsu, C. M. Huang, Y. L. Wang, H. W. Shih, Z. C. Wang, C. J. Wu, Structural and chemical trapping of short-lived flavin-oxide intermediates reveals substrate-directed reaction multiplicity, PROTEIN SCIENCE, vol. 29, 1655-1666, 2020
2020 K. Adhikari, I. W. Lo, C. L. Chen, Y. L. Wang, K. H. Lin, S. Malek Zadeh, R. Rattinam, Y. S. Li, C. J. Wu, Chemoenzymatic synthesis and biological evaluation for bioactive molecules derived from bacterial benzoyl coenzyme A ligase and plant type III polyketide synthase, BIOMOLECULES, vol. 10(5), 738, 2020
2020 S. Malek Zadeh, E. Astani, Z. C. Wang, K. Adhikari, R. Rattinam, Theoretical study of intermolecular interactions between critical residues of membrane protein MraYAA and Promising Antibiotic Muraymycin D2, ACS OMEGA, vol. 5(36), 22739–22749, 2020
2020 Y. M. Liu, T. H. Wu, Y. H. Chiu, H. Wang, S. Hsia, Y. L. Chan*, C. J. Wu*, Positive effects of preventive nutrition supplement on anticancer radiotherapy in lung cancer bearing mice, CANCERS, vol. 12(9), 2445, 2020
2019 C. M. Huang, S. Y. Lyu, K. H. Lin, C. L. Chen, M. H. Chen, H. W. Shih, N. H. Hsu, I. W. Lo, Y. L. Wang, Y. S. Li, C. J. Wu, T. L. Li*, Teicoplanin reprogrammed with the N-Acyl-glucosamine pharmacophore at the penultimate residue of aglycone acquires broad-spectrum antimicrobial activities effectively killing gram-positive and -negative pathogens, ACS INFECTIOUS DISEASES, vol. 5(3), 430-442, 2019
2019 H. W. Yeh, K. H. Lin, S. Y. Lyu, Y. S. Li, C. M. Huang, Y. L. Wang, H. W. Shih, N. S. Hsu, C. J. Wu, T. L. Li*, Biochemical and structural explorations for alpha-hydroxyacid oxidases reveal a 4-electron oxidative decarboxylation reaction, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 75(Pt 8), 733–742, 2019
2019 S. Y. Lyu, K. H. Lin, H. W. Yeh, Y. S. Li, C. M. Huang, Y. L. Wang, H. W. Shih, N. S. Hsu, C. J. Wu, T. L. Li*, The flavin mononucleotide cofactor in α-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate oxidation level, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 75(10), 918-929, 2019
2019 Y. M. Liu, Y. L. Chan, T. H. Wu, T. L. Li, S. Hsia, Y. H. Chiu*, C. J. Wu*, Antitumor, inhibition of metastasis and radiosensitizing effects of total nutrition formula on Lewis tumor-bearing mice, NUTRIENTS, vol. 11(8), 1944, 2019
2019 T. H. Huang, T. H. Wu, Y. H. Guo, T. L. Li, Y. L. Chan, C. J. Wu*, The concurrent treatment of Scutellaria baicalensis Georgi enhances the therapeutic efficacy of cisplatin but also attenuates chemotherapy-induced cachexia and acute kidney injury, JOURNAL OF ETHNOPHARMACOLOGY, vol. 243, 112075, 2019
2019 T. H. Wu, K. Y. Yeh, C. H. Wang, H. Wang, T. L. Li, Y. L. Chan, C. J. Wu*, The combination of Astragalus membranaceus and Angelica sinensis inhibits lung cancer and cachexia through its immunomodulatory function, JOURNAL OF ONCOLOGY, vol. 2019, 9206951, 2019
2019 C. M. Huang, S. Y. Lyu, K. H. Lin, C. L. Chen, M. H. Chen, H. W. Shih, N. H. Hsu, I. W. Lo, Y. L. Wang, Y. S. Li, C. J. Wu, Teicoplanin reprogrammed with the N-Acyl-glucosamine pharmacophore at the penultimate residue of aglycone acquires broad-spectrum antimicrobial activities effectively killing gram-positive and -negative pathogens, ACS INFECTIOUS DISEASES, vol. 5(3), 430-442, 2019
2019 H. W. Yeh, K. H. Lin, S. Y. Lyu, Y. S. Li, C. M. Huang, Y. L. Wang, H. W. Shih, N. S. Hsu, C. J. Wu, Biochemical and structural explorations for alpha-hydroxyacid oxidases reveal a 4-electron oxidative decarboxylation reaction, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 75(Pt 8), 733–742, 2019
2019 S. Y. Lyu, K. H. Lin, H. W. Yeh, Y. S. Li, C. M. Huang, Y. L. Wang, H. W. Shih, N. S. Hsu, C. J. Wu, The flavin mononucleotide cofactor in α-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate oxidation level, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 75(10), 918-929, 2019
2019 Y. M. Liu, Y. L. Chan, T. H. Wu, S. Hsia, Y. H. Chiu*, C. J. Wu*, Antitumor, inhibition of metastasis and radiosensitizing effects of total nutrition formula on Lewis tumor-bearing mice, NUTRIENTS, vol. 11(8), 1944, 2019
2019 T. H. Huang, T. H. Wu, Y. H. Guo, Y. L. Chan, C. J. Wu*, The concurrent treatment of Scutellaria baicalensis Georgi enhances the therapeutic efficacy of cisplatin but also attenuates chemotherapy-induced cachexia and acute kidney injury, JOURNAL OF ETHNOPHARMACOLOGY, vol. 243, 112075, 2019
2019 T. H. Wu, K. Y. Yeh, C. H. Wang, H. Wang, Y. L. Chan, C. J. Wu*, The combination of Astragalus membranaceus and Angelica sinensis inhibits lung cancer and cachexia through its immunomodulatory function, JOURNAL OF ONCOLOGY, vol. 2019, 9206951, 2019
2018 N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. Y. Lyu, L. J. Hsu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, The mesomeric effect of thiazolium on non-Kekule diradicals in Pichia stipitis transketolase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 57(7), 1802-1807, 2018
2018 N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. C. Ke, S. Y. Lyu, L. J. Hsu, Y. S. Li, S. C. Chen, K. C. Wang, T. L. Li*, Evidence of diradicals involved in the yeast transketolase catalyzed keto-transferring reactions, CHEMBIOCHEM, vol. 19(22), 2395-2402, 2018
2018 N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. Y. Lyu, L. J. Hsu, Y. C. Liu, C. Y. Chang, C. J. Wu, The mesomeric effect of thiazolium on non-Kekule diradicals in Pichia stipitis transketolase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 57(7), 1802-1807, 2018
2018 N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. C. Ke, S. Y. Lyu, L. J. Hsu, Y. S. Li, S. C. Chen, K. C. Wang, Evidence of diradicals involved in the yeast transketolase catalyzed keto-transferring reactions, CHEMBIOCHEM, vol. 19(22), 2395-2402, 2018
2017 Y. W. Chen, C. H. Lee, Y. L. Wang, T. L. Li, H. C. Chang*, Nanodiamonds as nucleating agents for protein crystallization, LANGMUIR, vol. 33(26), 6521-6527, 2017
2017 Y. W. Chen, C. H. Lee, Y. L. Wang, H. C. Chang*, Nanodiamonds as nucleating agents for protein crystallization, LANGMUIR, vol. 33(26), 6521-6527, 2017
2016 H. J. Chai, C. J. Wu, S. H. Yang, T. L. Li, P. B. Sun*, Peptides from hydrolysate of lantern fish (Benthosema pterotum) proved neuroprotective in vitro and in vivo, JOURNAL OF FUNCTIONAL FOODS, vol. 24, 438-449, 2016
2016 L. J. Hsu, N. S. Hsu, Y. L. Wang, C. J. Wu, T. L. Li*, Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality, PROTEIN ENGINEERING DESIGN & SELECTION, vol. 29(11), 513-522, 2016
2016 H. J. Chai, C. J. Wu, S. H. Yang, P. B. Sun*, Peptides from hydrolysate of lantern fish (Benthosema pterotum) proved neuroprotective in vitro and in vivo, JOURNAL OF FUNCTIONAL FOODS, vol. 24, 438-449, 2016
2016 L. J. Hsu, N. S. Hsu, Y. L. Wang, C. J. Wu, Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality, PROTEIN ENGINEERING DESIGN & SELECTION, vol. 29(11), 513-522, 2016
2015 H. Wang, T. L. Li, S. Hsia, I. L. Su, Y. L. Chan*, C. J. Wu*, Skeletal muscle atrophy is attenuated in tumor-bearing mice under chemotherapy by treatment with fish oil and selenium, ONCOTARGET, vol. 6(10), 7758-7773, 2015
2015 T. H. Huang, Y. H. Chiu, Y. L. Chan, Y. H. Chiu, H. Wang, K. C. Huang, T. L. Li, K. H. Hsu*, C. J. Wu*, Prophylactic administration of fucoidan represses cancer metastasis by inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in Lewis tumor-bearing mice, MARINE DRUGS, vol. 13, 1882-1900, 2015
2015 Y. C. Liu, Y. S. Li, S. Y. Lyu, L. J. Hsu, Y. H. Chen, Y. T. Huang, H. C. Chan, C. J. Huang, G. H. Chen, C. C. Chou, M. D. Tsai, T. L. Li*, Addendum: Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds, NATURE CHEMICAL BIOLOGY, vol. 11(5), 361-361, 2015
2015 T. H. Huang, Y. H. Chiu, Y. L. Chan, H. Wang, T. L. Li, Y. Chu, C. Y. Liu, C. T. Yang, T. Y. Lee, J. S. You, K. H. Hsu, C. J. Wu*, Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice, ONCOTARGET, vol. 6(28), 25741-25754, 2015
2015 H. Wang, S. Hsia, I. L. Su, Y. L. Chan*, C. J. Wu*, Skeletal muscle atrophy is attenuated in tumor-bearing mice under chemotherapy by treatment with fish oil and selenium, ONCOTARGET, vol. 6(10), 7758-7773, 2015
2015 T. H. Huang, Y. H. Chiu, Y. L. Chan, Y. H. Chiu, H. Wang, K. C. Huang, K. H. Hsu*, C. J. Wu*, Prophylactic administration of fucoidan represses cancer metastasis by inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in Lewis tumor-bearing mice, MARINE DRUGS, vol. 13, 1882-1900, 2015
2015 Y. C. Liu, Y. S. Li, S. Y. Lyu, L. J. Hsu, Y. H. Chen, Y. T. Huang, H. C. Chan, C. J. Huang, G. H. Chen, C. C. Chou, M. D. Tsai, Addendum: Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds, NATURE CHEMICAL BIOLOGY, vol. 11(5), 361-361, 2015
2015 T. H. Huang, Y. H. Chiu, Y. L. Chan, H. Wang, Y. Chu, C. Y. Liu, C. T. Yang, T. Y. Lee, J. S. You, K. H. Hsu, C. J. Wu*, Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice, ONCOTARGET, vol. 6(28), 25741-25754, 2015
2014 C. Y. Chang, S. Y. Lyu, Y. C. Liu, N. S. Hsu, C. C. Wu, C. F. Tang, K. H. Lin, J. Y. Ho, C. J. Wu, M. D. Tsai, T. L. Li*, Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 53(7), 1943-1948, 2014
2014 K. C. Wang, S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple-reaction complexes, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 70(5), 1401-1410, 2014
2014 X. W. Zou, Y. C. Liu, N. S. Hsu, C. J. Huang, S. Y. Lyu, H. C. Chan, C. Y. Chang, H. W. Yeh, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, Structure and mechanism of a non-heme iron-SAM dependent C-methyltransferase and its engineering to hydratase and O-methyltransferase, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 70(6), 1549-1560, 2014
2014 S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Huang, Y. H. Chiu, C. M. Huang, N. S. Hsu, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing vancomycin-resistant Enterococcus, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136(31), 10989-10995, 2014
2014 C. Y. Chang, S. Y. Lyu, Y. C. Liu, N. S. Hsu, C. C. Wu, C. F. Tang, K. H. Lin, J. Y. Ho, C. J. Wu, M. D. Tsai, Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 53(7), 1943-1948, 2014
2014 K. C. Wang, S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Wu, Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple-reaction complexes, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 70(5), 1401-1410, 2014
2014 X. W. Zou, Y. C. Liu, N. S. Hsu, C. J. Huang, S. Y. Lyu, H. C. Chan, C. Y. Chang, H. W. Yeh, K. H. Lin, C. J. Wu, M. D. Tsai, Structure and mechanism of a non-heme iron-SAM dependent C-methyltransferase and its engineering to hydratase and O-methyltransferase, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 70(6), 1549-1560, 2014
2014 S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Huang, Y. H. Chiu, C. M. Huang, N. S. Hsu, K. H. Lin, C. J. Wu, M. D. Tsai, Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing vancomycin-resistant Enterococcus, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136(31), 10989-10995, 2014
2013 H. Wang, Y. L. Chan, T. L. Li, B. A. Bauer, S. Hsia, C. H. Wang, J. S. Huang, H. M. Wang, K. Y. Yeh, T. H. Huang, C. J. Wu*, Reduction of splenic immunosuppressive cells and enhancement of anti-tumor immunity by synergy of fish oil and selenium yeast, PLOS ONE, vol. 8(1), e52912, 2013
2013 C. J. Chai, Y. L. Chan, T. L. Li, Y. K. Tsai, C. H. Wu, C. Y. Shiaua, C. J. Wu*, Evaluation of lanternfish (Benthosema pterotum) hydrolysates as antioxidants against hydrogen peroxide induced oxidative injury, FOOD RESEARCH INTERNATIONAL, vol. 54(2), 1409-1418, 2013
2013 H. Wang, Y. L. Chan, B. A. Bauer, S. Hsia, C. H. Wang, J. S. Huang, H. M. Wang, K. Y. Yeh, T. H. Huang, C. J. Wu*, Reduction of splenic immunosuppressive cells and enhancement of anti-tumor immunity by synergy of fish oil and selenium yeast, PLOS ONE, vol. 8(1), e52912, 2013
2013 C. J. Chai, Y. L. Chan, Y. K. Tsai, C. H. Wu, C. Y. Shiaua, C. J. Wu*, Evaluation of lanternfish (Benthosema pterotum) hydrolysates as antioxidants against hydrogen peroxide induced oxidative injury, FOOD RESEARCH INTERNATIONAL, vol. 54(2), 1409-1418, 2013
2012 Y. H. Chiu, Y. L. Chan, L. W. Tsai, T. L. Li, C. J. Wu*, Prevention of human enterovirus 71 infection by carrageenan, ANTIVIRAL RESEARCH, vol. 95, 128-134, 2012
2012 Y. H. Chiu, Y. L. Chan, T. L. Li, C. J. Wu*, Inhibition of Japanese encephalitis virus infection by the sulfated polysaccharide extracts from Ulva lactuca, MARINE BIOTECHNOLOGY, vol. 14, 468-478, 2012
2012 H. Wang, Y. L. Chan, T. L. Li, C. J. Wu*, Improving cachectic symptoms and immune strength of tumor-bearing mice in chemotherapy by a combination of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang, EUROPEAN JOURNAL OF CANCER, vol. 48, 1074-1084, 2012
2012 H. J. Chai, Y. L. Chan, T. L. Li, C. H. Wu, Y. C. Chen, C. Y. Shiau, C. J. Wu*, Composition characterization of Myctophids (Benthosema pterotum): antioxidation and safety evaluations for Myctophids protein hydrolysates, FOOD RESEARCH INTERNATIONAL, vol. 46, 118-126, 2012
2012 S. H. Chen, D. R. Hwang, G. H. Chen, N. S. Hsu, Y. T. Wu, T. L. Li*, C. H. Wong*, Engineering transaldolase in Pichia stipitis to improve bioethanol production, ACS CHEMICAL BIOLOGY, vol. 7(3), 481-486, 2012
2012 T. L. Li*, Y. C. Liu, S. Y. Lyu, Combining biocatalysis and chemoselective chemistries for glycopeptide antibiotics modification, CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 16, 170-178, 2012
2012 H. C. Wu, Y. S. Li, Y. C. Liu, S. Y. Lyu, C. J. Wu, T. L. Li*, Chain elongation and cyclization in type III PKS DpgA, CHEMBIOCHEM, vol. 13(6), 862-871, 2012
2012 T. L. Lin, F. L. Yang, A. S. Yang, H. P. Peng, T. L. Li, M. D. Tsai, S. H. Wu, J. T. Wang*, Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide, PLOS ONE, vol. 7(10), e46783, 2012
2012 Y. H. Chiu, Y. L. Chan, L. W. Tsai, C. J. Wu*, Prevention of human enterovirus 71 infection by carrageenan, ANTIVIRAL RESEARCH, vol. 95, 128-134, 2012
2012 Y. H. Chiu, Y. L. Chan, C. J. Wu*, Inhibition of Japanese encephalitis virus infection by the sulfated polysaccharide extracts from Ulva lactuca, MARINE BIOTECHNOLOGY, vol. 14, 468-478, 2012
2012 H. Wang, Y. L. Chan, C. J. Wu*, Improving cachectic symptoms and immune strength of tumor-bearing mice in chemotherapy by a combination of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang, EUROPEAN JOURNAL OF CANCER, vol. 48, 1074-1084, 2012
2012 H. J. Chai, Y. L. Chan, C. H. Wu, Y. C. Chen, C. Y. Shiau, C. J. Wu*, Composition characterization of Myctophids (Benthosema pterotum): antioxidation and safety evaluations for Myctophids protein hydrolysates, FOOD RESEARCH INTERNATIONAL, vol. 46, 118-126, 2012
2012 S. H. Chen, D. R. Hwang, G. H. Chen, N. S. Hsu, Y. T. Wu, C. H. Wong*, Engineering transaldolase in Pichia stipitis to improve bioethanol production, ACS CHEMICAL BIOLOGY, vol. 7(3), 481-486, 2012
2012 Y. C. Liu, S. Y. Lyu, Combining biocatalysis and chemoselective chemistries for glycopeptide antibiotics modification, CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 16, 170-178, 2012
2012 H. C. Wu, Y. S. Li, Y. C. Liu, S. Y. Lyu, C. J. Wu, Chain elongation and cyclization in type III PKS DpgA, CHEMBIOCHEM, vol. 13(6), 862-871, 2012
2012 T. L. Lin, F. L. Yang, A. S. Yang, H. P. Peng, M. D. Tsai, S. H. Wu, J. T. Wang*, Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide, PLOS ONE, vol. 7(10), e46783, 2012
2011 H. C. Chan, Y. T. Huang, S. Y. Lyu, C. J. Huang, Y. S. Li, Y. C. Liu, C. C. Chou, M. D. Tsai, T. L. Li*, Regioselective deacetylation based on teicoplanin-complexed Orf2* crystal structures, MOLECULAR OMICS (MOLECULAR BIOSYSTEMS), vol. 7(4), 1224-1231, 2011
2011 C. J. Wu, H. Wang, Y. L. Chan, T. L. Li, Passive immune-protection of small abalone against Vibrio alginolyticus infection by anti-Vibrio IgY-encapsulated feed, FISH & SHELLFISH IMMUNOLOGY, vol. 30, 1042-1048, 2011
2011 Y. C. Liu, Y. S. Li, S. Y. Lyu, L. J. Hsu, Y. H. Chen, Y. T. Huang, H. C. Chan, C. J. Huang, G. H. Chen, C. C. Chou, M. D. Tsai, T. L. Li*, Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds, NATURE CHEMICAL BIOLOGY, vol. 7, 304-309, 2011
2011 H. Wang, Y. J. Lai, Y. L. Chan, T. L. Li, C. J. Wu*, Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia, CANCER LETTERS, vol. 305(1):40-49, 2011
2011 J. Y. Ho, T. L. Lin, A. Lee, A. N. Cheng, C. Y. Li, M. C. Chen, S. H. Wu, J. T. Wang*, T. L. Li*, M. D. Tsai*, Functions of some capsular polysaccharide biosynthetic genes in Klebsiella pneumoniae NTUH K-2044, PLOS ONE, vol. 6(7), e21664, 2011
2011 H. C. Chan, Y. T. Huang, S. Y. Lyu, C. J. Huang, Y. S. Li, Y. C. Liu, C. C. Chou, M. D. Tsai, Regioselective deacetylation based on teicoplanin-complexed Orf2* crystal structures, MOLECULAR OMICS (MOLECULAR BIOSYSTEMS), vol. 7(4), 1224-1231, 2011
2011 C. J. Wu, H. Wang, Y. L. Chan, Passive immune-protection of small abalone against Vibrio alginolyticus infection by anti-Vibrio IgY-encapsulated feed, FISH & SHELLFISH IMMUNOLOGY, vol. 30, 1042-1048, 2011
2011 Y. C. Liu, Y. S. Li, S. Y. Lyu, L. J. Hsu, Y. H. Chen, Y. T. Huang, H. C. Chan, C. J. Huang, G. H. Chen, C. C. Chou, M. D. Tsai, Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds, NATURE CHEMICAL BIOLOGY, vol. 7, 304-309, 2011
2011 H. Wang, Y. J. Lai, Y. L. Chan, C. J. Wu*, Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia, CANCER LETTERS, vol. 305(1):40-49, 2011
2011 J. Y. Ho, T. L. Lin, A. Lee, A. N. Cheng, C. Y. Li, M. C. Chen, S. H. Wu, J. T. Wang*, M. D. Tsai*, Functions of some capsular polysaccharide biosynthetic genes in Klebsiella pneumoniae NTUH K-2044, PLOS ONE, vol. 6(7), e21664, 2011
2010 H. J. Chai, J. H. Li, H. N. Huang, T. L. Li, Y. L. Chan, C. Y. Shiau, C. J. Wu*, Effects of sizes and conformations of fish scale collagen peptides (FSCPs) on facial skin qualities and transdermal penetration efficiency, JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, vol. 2010, 757301, 2010
2010 H. J. Chai, J. H. Li, H. N. Huang, Y. L. Chan, C. Y. Shiau, C. J. Wu*, Effects of sizes and conformations of fish scale collagen peptides (FSCPs) on facial skin qualities and transdermal penetration efficiency, JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, vol. 2010, 757301, 2010
2009 T. L. Li*, D. Spiteller, J. B. Spencer, Identification of a pentaketide stilbene produced by a type III polyketide synthase from Pinus sylvestris and characterisation of free coenzyme A intermediates, CHEMBIOCHEM, vol. 10, 896-901, 2009
2009 J. Y. Cheng, H. N. Huang, W. C. Tseng, T. L. Li, Y. L. Chan, K. C. Cheng, C. J. Wu*, Transcutaneous immunization by lipoplex-patch based DNA vaccines is effective vaccination against Japanese encephalitis virus infection, JOURNAL OF CONTROLLED RELEASE, vol. 135, 242-249, 2009
2009 H. N. Huang, T. L. Li, Y. L. Chan, C. L. Chen, C. J. Wu*, Transdermal immunization with low-pressure-gene-gun mediated chitosan-based DNA vaccines against Japanese encephalitis virus, BIOMATERIALS, vol. 30(30), 6017-6025, 2009
2009 Y. T. Huang, S. Y. Lyu, P. H. Chuang, N. S. Hsu, Y. S. Li, H. C. Chan, C. J. Huang, Y. C. Liu, C. J. Wu, W. B. Yang, T. L. Li*, In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-b-methylphenylalanine in glycopeptide antibiotic mannopeptimycin, CHEMBIOCHEM, vol. 10, 2480-2487, 2009
2009 D. Spiteller, J. B. Spencer, Identification of a pentaketide stilbene produced by a type III polyketide synthase from Pinus sylvestris and characterisation of free coenzyme A intermediates, CHEMBIOCHEM, vol. 10, 896-901, 2009
2009 J. Y. Cheng, H. N. Huang, W. C. Tseng, Y. L. Chan, K. C. Cheng, C. J. Wu*, Transcutaneous immunization by lipoplex-patch based DNA vaccines is effective vaccination against Japanese encephalitis virus infection, JOURNAL OF CONTROLLED RELEASE, vol. 135, 242-249, 2009
2009 H. N. Huang, Y. L. Chan, C. L. Chen, C. J. Wu*, Transdermal immunization with low-pressure-gene-gun mediated chitosan-based DNA vaccines against Japanese encephalitis virus, BIOMATERIALS, vol. 30(30), 6017-6025, 2009
2009 Y. T. Huang, S. Y. Lyu, P. H. Chuang, N. S. Hsu, Y. S. Li, H. C. Chan, C. J. Huang, Y. C. Liu, C. J. Wu, W. B. Yang, In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-b-methylphenylalanine in glycopeptide antibiotic mannopeptimycin, CHEMBIOCHEM, vol. 10, 2480-2487, 2009
2007 Y. S. Li, J. Y. Ho, C. C. Huang, S. Y. Lyu, C. Y. Lee, Y. T. Huang, C. J. Wu, H. C. Chan, C. J. Huang, N. S. Hsu, M. D. Tsai, T. L. Li*, A unique flavin mononucleotide-linked primary alcohol oxidase for glycopeptide A40926 maturation, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, 13384-13385, 2007
2007 Y. S. Li, J. Y. Ho, C. C. Huang, S. Y. Lyu, C. Y. Lee, Y. T. Huang, C. J. Wu, H. C. Chan, C. J. Huang, N. S. Hsu, M. D. Tsai, A unique flavin mononucleotide-linked primary alcohol oxidase for glycopeptide A40926 maturation, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, 13384-13385, 2007
2006 F. Huang, S. F. Haydock, D. Spiteller, T. Mironenko, T. L. Li, P. F. Leadlay, D. O'Hagan, J. B. Spencer*, The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A., CELL CHEMICAL BIOLOGY (CHEMISTRY & BIOLOGY), vol. 13(5), 475-484, 2006
2006 J. Y. Ho, Y. T. Huang, C. J. Wu, Y. S. Li, M. D. Tsai, T. L. Li*, Glycopeptide Biosynthesis: Dbv21/Orf2* from dbv/tcp Gene Clusters Are N-Ac-Glm Teicoplanin Pseudoaglycone Deacetylases and Orf15 from cep Gene Cluster Is a Glc-1-P Thymidyltransferase, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128(42), 13694-13695, 2006
2006 C. J. Wu*, T. L. Li, H. W. Huang, Y. L. Chan, M. H. Tao, Development of an effective Japanese encephalitis virus-specific DNA vaccine, MICROBES AND INFECTION, vol. 8, 2578-2586, 2006
2006 F. Huang, S. F. Haydock, D. Spiteller, T. Mironenko, P. F. Leadlay, D. O'Hagan, J. B. Spencer*, The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A., CELL CHEMICAL BIOLOGY (CHEMISTRY & BIOLOGY), vol. 13(5), 475-484, 2006
2006 J. Y. Ho, Y. T. Huang, C. J. Wu, Y. S. Li, M. D. Tsai, Glycopeptide Biosynthesis: Dbv21/Orf2* from dbv/tcp Gene Clusters Are N-Ac-Glm Teicoplanin Pseudoaglycone Deacetylases and Orf15 from cep Gene Cluster Is a Glc-1-P Thymidyltransferase, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128(42), 13694-13695, 2006
2006 C. J. Wu*, H. W. Huang, Y. L. Chan, M. H. Tao, Development of an effective Japanese encephalitis virus-specific DNA vaccine, MICROBES AND INFECTION, vol. 8, 2578-2586, 2006
2004 T. L. Li, F. Huang, S. F. Haydock*, T. Mironenko, P. F. Leadlay, J. B. Spencer*, Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase, CELL CHEMICAL BIOLOGY (CHEMISTRY & BIOLOGY), vol. 11(1), 107-119, 2004
2004 F. Huang, S. F. Haydock*, T. Mironenko, P. F. Leadlay, J. B. Spencer*, Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase, CELL CHEMICAL BIOLOGY (CHEMISTRY & BIOLOGY), vol. 11(1), 107-119, 2004
2002 T. L. Li*, Y. J. Chung-Wang, Y. C. Shih, Determination and confirmation of chloramphenicol residues in swine muscle and liver, JOURNAL OF FOOD SCIENCE, vol. 67(1), 21-28, 2002
2002 Y. J. Chung-Wang, Y. C. Shih, Determination and confirmation of chloramphenicol residues in swine muscle and liver, JOURNAL OF FOOD SCIENCE, vol. 67(1), 21-28, 2002
2001 W. C. Lee, T. L. Li*, P. C. Chang, S. S. Chou, High performance liquid chromatographic determination of maleic hydrazide residue in potatoes, JOURNAL OF FOOD AND DRUG ANALYSIS, vol. 9(3), 167-172, 2001
2001 T. L. Li, W. C. Lee*, P. C. Chang, S. S. Chou, High performance chromatographic determination of asulam residue in agricultural products, JOURNAL OF FOOD AND DRUG ANALYSIS, vol. 9 (1), 40-44, 2001
2001 T. L. Li, O. W. Choroba, E. H. Charles, A. M. Sandercock, D. H. Williams, J. B. Spencer*, Characterisation of a hydroxymandelate oxidase involved in the biosynthesis of two unusual amino acids occurring in the vancomycin group of antibiotics, CHEMICAL COMMUNICATIONS, vol. -18, 1752-1753, 2001
2001 T. L. Li, O. W. Choroba, H. Hong, D. H. Williams, J. B. Spencer*, Biosynthesis of the vancomycin group of antibiotics: characterisation of a type III polyketide synthase in the pathway to (S)-3,5-dihydroxyphenylglycine, CHEMICAL COMMUNICATIONS, vol. 20, 2156-2157, 2001
2001 W. C. Lee, P. C. Chang, S. S. Chou, High performance liquid chromatographic determination of maleic hydrazide residue in potatoes, JOURNAL OF FOOD AND DRUG ANALYSIS, vol. 9(3), 167-172, 2001
2001 W. C. Lee*, P. C. Chang, S. S. Chou, High performance chromatographic determination of asulam residue in agricultural products, JOURNAL OF FOOD AND DRUG ANALYSIS, vol. 9 (1), 40-44, 2001
2001 O. W. Choroba, E. H. Charles, A. M. Sandercock, D. H. Williams, J. B. Spencer*, Characterisation of a hydroxymandelate oxidase involved in the biosynthesis of two unusual amino acids occurring in the vancomycin group of antibiotics, CHEMICAL COMMUNICATIONS, vol. -18, 1752-1753, 2001
2001 O. W. Choroba, H. Hong, D. H. Williams, J. B. Spencer*, Biosynthesis of the vancomycin group of antibiotics: characterisation of a type III polyketide synthase in the pathway to (S)-3,5-dihydroxyphenylglycine, CHEMICAL COMMUNICATIONS, vol. 20, 2156-2157, 2001
2000 T. L. Li, J. M. King, Y. B. Min*, Quenching mechanisms and kinetics of carotenoids in riboflavin photosensitized singlet oxygen oxidation of vitamin D-2, JOURNAL OF FOOD BIOCHEMISTRY, vol. 24 (6), 477-492, 2000
2000 J. M. King, Y. B. Min*, Quenching mechanisms and kinetics of carotenoids in riboflavin photosensitized singlet oxygen oxidation of vitamin D-2, JOURNAL OF FOOD BIOCHEMISTRY, vol. 24 (6), 477-492, 2000
1998 W. C. Lee, T. L. Li*, W. J. Cheng, P. C. Chang, S. S. Chou, Survey of nicotine and tar yields of domestic and imported cigarettes, JOURNAL OF FOOD AND DRUG ANALYSIS, vol. 6 (4), 691-701, 1998
1998 T. L. Li*, D. B. Min*, Stability and photochemistry of vitamin D-2 in model system, JOURNAL OF FOOD SCIENCE, vol. 63 (3), 413-417, 1998
1998 D. B. Min*, T. L. Li, H. O. Lee, Effects of processing steps on the contents of minor compounds and oxidation of soybean oil, ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 434, 161-180, 1998
1998 W. C. Lee, W. J. Cheng, P. C. Chang, S. S. Chou, Survey of nicotine and tar yields of domestic and imported cigarettes, JOURNAL OF FOOD AND DRUG ANALYSIS, vol. 6 (4), 691-701, 1998
1998 D. B. Min*, Stability and photochemistry of vitamin D-2 in model system, JOURNAL OF FOOD SCIENCE, vol. 63 (3), 413-417, 1998
1998 D. B. Min*, H. O. Lee, Effects of processing steps on the contents of minor compounds and oxidation of soybean oil, ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 434, 161-180, 1998
年度 書名
2022 新編食品生物技術 2nd, 生物技術的工具, 華格那, 2-1~2-44, Aug. 2022
2022 新編食品生物技術 2nd, 生物技術的工具, 華格那, 2-1~2-44, Aug. 2022
2016 食品生物技術, 生物技術的工具, 華格那, 2-1~2-44, Sep. 2016
2016 食品生物技術, 生物技術的工具, 華格那, 2-1~2-44, Sep. 2016
2007 食品生物技術, 生物技術的工具, 華格那, 2-1~2-44, Feb. 2007
2007 食品生物技術, 生物技術的工具, 華格那, 2-1~2-44, Feb. 2007
公開日期 提名
2025/07 李宗璘 and Li TL*,"醣胜肽類抗生素生合成酵素之探討," 中央研究院週報, 知識天地, Jul. 2025
2025/07 李宗璘, Liu YC, and Li TL*,"截取抗生素氧化中間產物以發展新型態抗生素," 國家同步輻射研究中心簡訊, Jul. 2025
2025/07 李宗璘, Chang CY, and Li TL*,"探討抗生素Streptothricin生合成路徑及其酵素作用機轉," 國家同步輻射研究中心簡訊, Jul. 2025