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MONO-GLCNAC-DECORATED SPIKE VACCINE IS HIGHLY EFFECTIVE AGAINST COVID-19 VARIANTS

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in more than 440 million confirmed cases and over 6 million deaths so far. Although there are COVID-19 vaccines available, viruses constantly change through mutations. Key questions remain about how quickly the variants can spread, their potential to evade immunity and how effective the vaccines...

MRNA VACCINE OF SARS-COV-2 SPIKE PROTEIN WITH DELETION OF MULTIPLE GLYCOSITES IS BROADLY PROTECTIVE AGAINST VARIANTS OF CONCERN

Vaccination is an effective strategy to control the spread of SARS-CoV-2. However, current vaccines may lose their efficacy because of the high mutation rate of SARS-CoV-2. To overcome this problem, development of a universal SARS-CoV-2 vaccine with broad protection against the current and upcoming variants is needed.

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