年度	論文名稱
2022	Huang CY, Nicholson MW, Wang JY, Ting CY, Tsai MH, Cheng YC, Liu CL, Chan DZH, Lee YC, Hsu CC, Hsu YH, Yang CF, Chang CMC, Ruan SC, Lin PJ, Lin JH, Chen LL, Hsieh ML, Cheng YY, Hsu WT, Lin YL, Chen CH, Hsu YH, (Wu YT, Hacker TA, Wu JC, Kamp TJ, Hsieh PCH, Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons, CELL REPORTS, vol. 39(1), 110643, 2022
2022	Chen WA, Chen YH, Hsieh CY, Hung PF, Chen CW, Chen CH, Lin JL, Cheng TR, Hsu TL, (Wu YT, Shen CN, Cheng WC, Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents, CHEMICAL SCIENCE, vol. 13(21), 6233-6243, 2022
2022	Nicholson MW, Huang CY, Wang JY, Ting CY, Cheng YC, Chan DZH, Lee YC, Hsu CC, Hsu YH, Chang CMC, Hsieh ML, Cheng YY, Lin YL, Chen CH, (Wu YT, Hacker TA, Wu JC, Kamp TJ, Hsieh PCH, Cardio- and Neurotoxicity of Selected Anti-COVID-19 Drugs, PHARMACEUTICALS, vol. 15(6), 765, 2022
2022	Chuang HC, Liu MF, Wu HY, Cheng TR, Fang JM, Photoaffinity labeling of benzophenone-containing salicylanilide compounds to give an insight into the mechanism in disrupting peptidoglycan formation, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 67, 116819, 2022
2021	Jan JT, Cheng TR, Juang YP, Ma HH, (Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118 (5), e2021579118, 2021
2020	Woodring JL, Lu SH, Krasnova L, Wang SC, Chen JB, Chou CC, Huang YC, Cheng TR, (Wu YT, Chen YH, Fang JM, Tsai MD, Wong CH, Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein., Journal of medicinal chemistry, vol. 63(1), 205-215, 2020
2020	Chang YH, Wu JC, Yu HM, Hsu HT, (Wu YT, Yu AL, Yu CT, Wong CH, Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction., Chemical communications (Cambridge, England), vol. 56(43), 5827-5830, 2020
2015	Tsai CC, Lin CR, Tsai HY, Chen CJ, Li WT, Yu HM, Ke YY, Hsieh WY, Chang CY, Chen ST, Wong CH, The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling, JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 290(19), 11935, 2015
2013	Wang SH, Kuo SC, Yu J, HotLig: a molecular surface-directed approach to scoring protein-ligand interactions, JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 53(8), 2181-2195, 2013
2013	Cheng TJ, Chan TH, Tsou EL, Chang SY, Yun WY, Yang PJ, Cheng WC, From Natural Product-Inspired Pyrrolidine Scaffolds to the Development of New Human Golgi α-Mannosidase II Inhibitors, Chemistry-An Asian Journal, vol. 8(11), 2600-2604, 2013
2013	Bryk R, Arango N, Maksymiuk C, Balakrishnan A, Wong CH, Masquelin T, Hipskind P, Lima CD, Nathan C, Lipoamide Channel-Binding Sulfonamides Selectively Inhibit Mycobacterial Lipoamide Dehydrogenase, Biochemistry, vol. 52(51), 9375-9384, 2013
2013	Thi Thanh Hanh Nguyen, Sun Lee, Hsi-Kai Wang, Hsin-Yen Chen, Ying-Ta Wu, Simon C. Lin, Do-Won Kim, Doman Kim, In Vitro Evaluation of Novel Inhibitors against the NS2B-NS3 Protease of Dengue Fever Virus Type 4, MOLECULES, vol. 18(12), 15600-15612, 2013
2012	Chen SH, Hwang DR, Chen GH, Hsu NS, Li TL, Wong CH, Engineering Transaldolase in Pichia stipitis to Improve Bioethanol Production, ACS CHEMICAL BIOLOGY, vol. 7(3), 481-486, 2012
2011	Shen YF, Chen YH, Chu SY, Lin MI, Hsu HT, Wu PY, Wu CJ, Liu HW, Lin FY, Lin G, Hsu PH, Yang AS, Cheng YS, Wong CH, Tsai MD, E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108, 16515-16520, 2011
2010	Hsin-Yen Chen · Mason Hsiung · Hurng-Chun Lee · Eric Yen · Simon C. Lin· Ying-Ta Wu*, GVSS: A High Throughput Drug Discovery Service of Avian Flu and Dengue Fever for EGEE and EUAsiaGrid, Journal of Grid Computing, vol. 8, 529-541, 2010
2010	Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, Lin-Chu SY, Chen YH, Wu CY, Lai MM, Cheng WC, Tsai MD, High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 107(45), 19151-19156, 2010
2010	Cheng TJ, Yang ST, Lo KH, Chen SK, Chen YH, Huang WI, Yuan CH, Guo CW, Huang LY, Chen KT, Shih HW, Cheng YS, Cheng WC, Wong CH, High-throughput identification of antibacterials against methicillinresistant Staphylococcus aureus (MRSA) and the transglycosylase, BIOORGAN MED CHEM, vol. 18(24), 8512-8529, 2010
2009	Wang SY, Su CY, Lin M, Huang SY, Huang WI, Wang CC, Cheng TJ, Yu HM, Ren CT, Wu CY, Wong CH, Cheng YS, HA-pseudotyped retroviral vectors for influenza antagonist screening, JOURNAL OF BIOMOLECULAR SCREENING, vol. 14(3), 294-302, 2009
2009	Breton V, da Costa AL, de Vlieger P, Kim YM, Maigne L, Reuillon R, Sarramia D, Truong NH, Nguyen HQ, Kim D, Innovative in silico approaches to address avian flu using grid technology, Infect Disord Drug Targets, vol. 9, 358-365, 2009
2008	Tu S, Teng YC, Yuan C, Chan MY, Cheng AN, Lin PH, Juan LJ, Tsai MD, The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif, NATURE STRUCTURAL & MOLECULAR BIOLOGY, vol. 15(4), 419-421, 2008
2007	Liu LT, Yuan TT, Liu HH, Chen SF, Synthesis and biological evaluation of substituted 6-alkynyl-4-anilinoquinazoline derivatives as potent EGFR inhibitors, Bioorg Med Chem Lett., vol. 17, 6373-6377, 2007
2006	C. Y. Wu, K. Y. King, C. J. Kuo, J. M. Fang, M. Y. Ho, C. L. Liao, J. J. Shie, P. H. Liang, C. H. Wong, Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease, Chem Biol, vol. 13, 261-268, 2006
2006	Liang PH, Cheng WC, Lee YL, Yu HP, Lin YL, Wong CH, Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis, Chembiochem., vol. 7, 165-173, 2006
2006	Ho CW, Lin YN, Chang CF, Li ST, Wu CY, Chang CF, Liu SW, Li YK, Lin CH, Discovery of different types of inhibition between the human and thermotoga maritima alpha-fucosidases by fuconojirimycin-based derivatives, Biochemistry, vol. 45, 5695-702, 2006
2006	Lee HC, Salzemann J, Jacq N, Chen HY, Ho LY, Merelli I, Milanesi L, Breton V, Lin SC, Grid-enabled High-throughput in silico Screening against Influenza A Neuraminidase, IEEE TRANSACTIONS ON NANOBIOSCIENCE, vol. 5(4), 288-295, 2006
2005	L. R. Chen, Y. C. Wang, Y. W. Lin, S. Y. Chou, S. F. Chen, L. T. Liu, C. J. Kuo, T. S. Chen, S. H. Juang, Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors, Bioorg Med Chem Lett, vol. 15, 3058-3062, 2005
2005	J. J. Shie, J. M. Fang, T.H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, J.T. Jan, Y. S. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, 5240-5252, 2005
2005	Shie, J. J., Fang, J. M., Kuo, C. J., Kuo, T. H., Liang, P. H., Huang, H. J., Yang, W. B., Lin, C. H., Chen, J. L., Wu, Y. T., Wong, C. H., Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease., J Med Chem, vol. 48(13), 4469-4473, 2005