Focus News
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PDAC tumor cell-fibroblast interactions promote metastasis via Homophilic ATP1A1 Binding
Pancreatic ductal adenocarcinoma (PDAC) is responsible for more than 90% of pancreatic cancer cases, just 11% of PDAC patients live for at least five years after their diagnosis. It is seldom detected at its early stages when it's most curable.
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The critical point to treatment from the inside out: hybrid inorganic/organic nanoparticles with exosomes for cancer treatment
Since James E. Rothman, Randy W. Schekman, and Thomas C. Sudhof won the Nobel Prize in 2013 for revealing intracellular vesicles’ transport regulation mechanism, such as exosomes, which initially believed the primary function was only exosomes that transport cellular waste.
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Learning from nature: StnK3 is the epimerase controlling β-methyl amino acid stereochemistry
Natural products are a significant source of structurally diverse bioactive compounds for pharmaceutical, cosmetic, and food applications. Bioactive compounds often carry desired biological activities, such as anti-inflammation, anticancer, analgesics, and pain killing.