News
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2022-03The critical point to treatment from the inside out: hybrid inorganic/organic nanoparticles with exosomes for cancer treatment
Since James E. Rothman, Randy W. Schekman, and Thomas C. Sudhof won the Nobel Prize in 2013 for revealing intracellular vesicles’ transport regulation mechanism, such as exosomes, which initially believed the primary function was only exosomes that transport cellular waste. -
2022-03Learning from nature: StnK3 is the epimerase controlling β-methyl amino acid stereochemistry
Natural products are a significant source of structurally diverse bioactive compounds for pharmaceutical, cosmetic, and food applications. Bioactive compounds often carry desired biological activities, such as anti-inflammation, anticancer, analgesics, and pain killing. -
2022-03FAS receptor regulates NOTCH activity through ERK-JAG1 axis activation and controls oral cancer stemness ability and pulmonary metastasis
Michael Hsiao
Cell Death Discovery -
2022-03Mono-GlcNAc-decorated spike vaccine is highly effective against COVID-19 variants
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2022-03Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models
Che Ma, Kuo-I Lin, Chi-Huey Wong
Science Translational Medicine -
2022-02Progress and Viewpoints of Multifunctional Composite Nanomaterials for Glioblastoma Theranostics
Michael Hsiao
Pharmaceutics -
2022-02mRNA vaccine of SARS-CoV-2 spike protein with deletion of multiple glycosites is broadly protective against variants of concern
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2022-02Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine
Chi-Huey Wong
PNAS -
2022-02Dr. Chi-Huey Wong Honored as 2022 Recipient of the Tetrahedron Prize
